Most models in the S Classic series have a mahogany body which is inspired by the thin-edged S series shape but is slightly thicker and more rounded. This body can be described as a cross between the S series and the Radius series designs. The controls of the S Classic guitars are mounted from the top to significantly reduce the size of the control cavity and the reduction in wood that requires.
This new body is bolted to a slightly thicker neck than is found on the S series with a different headstock with a 3-on-a-side tuner configuration. The S Classic neck also has a shorter 25.1" (638mm) scale.
However there are a couple of outliers in the series that don't hew to the typical formula outlined above. The J Custom SC-GUT and the standard series SC500N are unique among Ibanez solid body electric guitars in that they employ nylon strings and piezo pickups. The SCR220 has a Radius series body with an S Classic neck. Finally the SCA220 features a body similar to that of the SA series, specifically the GSA60.