The JS2480 features a basswood body bolted to a maple and bubinga neck with a 24-fret rosewood fingerboard with mother of pearl dot position markers. Components include an Edge double locking tremolo bridge with a locking nut and an Ultralite tremolo arm, a DiMarzio Satchur8 humbucking pickup in the bridge position and Gotoh tuning machines.
The defining feature of this model is the Sustainiac driver neck pickup. This is the first Ibanez production model to incorporate this technology. The Sustainiac feature is controlled by a push-pull on/off switch on the tone control as well as a 3-way toggle with three settings: harmonic, normal or mixed. Additionally the volume control has a push-pull switch which activates a high-pass filter.
It was initially offered only in Muscle Car Red, but a new White finish was introduced in mid-2025.
The JS1CR30 is a similar model with a chrome finish which commemorated the 30th anniversary of the JS series in 2018. The JS1CR is another similar chrome guitar introduced in 2019.